The city contains mosaics from the 4th century A.D., a stone bridge with nine arches, city wall ruins in Akropal, the Havraniye Caravanserai, built in 1542, and a little mosque wih one dome.
Misis, near the Ceyhan River, is the second stop on the historical SilkRoad after Adana. The history of Misis possibly starts with its tumulus (6000 B.C.).
It was controlled by Hittites, Assyrians, Macedonians, and after became an important center in the Roman and Byzantine periods. It's said that Mopsus, one of the heroes of Troy, established in Misis.